Multiplex epitope mapping using bacterial surface display reveals both linear and conformational epitopes
نویسندگان
چکیده
منابع مشابه
Multiplex epitope mapping using bacterial surface display reveals both linear and conformational epitopes
As antibody-based diagnosis and therapy grow at an increased pace, there is a need for methods which rapidly and accurately determine antibody-antigen interactions. Here, we report a method for the multiplex determination of antibody epitopes using bacterial cell-surface display. A protein-fragment library with 10(7) cell clones, covering 60 clinically-relevant protein targets, was created and ...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2012
ISSN: 2045-2322
DOI: 10.1038/srep00706